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Editorial Board
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iii
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| Reviews |
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Adenosine improves post-procedural coronary flow but not clinical outcomes in patients with acute coronary syndrome: A meta-analysis of randomized trials
07 December 2011
Abstract: Aims: Adjunctive therapy with adenosine has been shown to improve coronary flow in patients with acute coronary syndromes (ACS); it is unclear, however, whether adenosine can effectively red...
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Eliano Pio Navarese,
Antonino Buffon,
Felicita Andreotti,
Paul Alfred Gurbel,
Marek Kozinski,
Aldona Kubica,
Giuseppe Musumeci,
Alberto Cremonesi,
Luigi Tavazzi,
Jacek Kubica,
Fausto Castriota
et al.
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1-7
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The urokinase system in the pathogenesis of atherosclerosis
05 December 2011
Abstract: Atherogenesis refers to the development of atheromatous plaques in the inner lining of the arteries. These atherosclerotic lesions are characterized by accumulation of monocyte-derived macro...
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Bianca Fuhrman
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8-14
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Statins as a possible cause of inflammatory and necrotizing myopathies
12 December 2011
Abstract: Background: Hydroxy-methyl-glutaryl Co-A reductase (HMGCR) inhibitors or statins are a well recognized cause of a variety of skeletal myopathic effects which generally resolve on stopping th...
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Santosh Padala,
Paul D. Thompson
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15-21
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| Invited Commentaries |
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The growing interest of fibrin imaging in atherosclerosis
06 March 2012
Atherosclerosis is a systemic, chronic and progressive inflammatory disease that is characterised by the build-up of lipid-rich plaques within the walls of large arteries. Atherosclerotic lesions (ath...
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Gisèle Clofent-Sanchez,
Marie-Josée Jacobin-Valat,
Jeanny Laroche-Traineau
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22-25
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Endogenous hyperinsulinaemia and exogenous insulin: A common theme between atherosclerosis, increased cancer risk and other morbidities
05 March 2012
Insulin is the oldest treatment for hyperglycaemia, and its value in type 1 diabetes is indisputable. However, although the goal of reducing microvascular and macrovascular complications remains the s...
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Sarah E. Holden,
Craig J. Currie
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26-28
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| Hypothesis |
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Author(s) |
Pages |
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Dual effects of statins therapy in systemic lupus erythematosus and SLE-related atherosclerosis: The potential role for regulatory T cells
14 March 2012
Abstract: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease associated with accelerated atherosclerosis independent of traditional risk factors. Statins, the 3-hydroxy-3-methyl-gl...
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Haiyan Tu,
Qi Li,
Shilong Xiang,
Hong Jiang,
Youying Mao,
Zhangfei Shou,
Jianghua Chen
et al.
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29-33
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| Basic Research |
| Vascular Biology, Hemostasis, Oxidative Stress |
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Author(s) |
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Leonurine protects against tumor necrosis factor-α-mediated inflammation in human umbilical vein endothelial cells
13 February 2012
Abstract: Objective: Leonurine, a bioactive alkaloid compound in Herba leonuri, has various pharmacological activities, including antioxidant and anti-apoptotic capacities. This study was conducted to...
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Xinhua Liu,
Lilong Pan,
Xianli Wang,
Qihai Gong,
Yi Zhun Zhu
et al.
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34-42
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In vivo assessment of intraplaque and endothelial fibrin in ApoE−/− mice by molecular MRI
30 January 2012
Highlights: ► A fibrin-targeted contrast agent (FTCA) allows in vivo imaging of atherosclerosis. ► Late stage plaques show the strongest signal enhancement after FTCA administration. ► FTCA enables th...
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Marcus R. Makowski,
Sarah C. Forbes,
Ulrike Blume,
Alice Warley,
Christian H.P. Jansen,
Andreas Schuster,
Andrea J. Wiethoff,
René M. Botnar
et al.
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43-49
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Coptisine exert cardioprotective effect through anti-oxidative and inhibition of RhoA/Rho kinase pathway on isoproterenol-induced myocardial infarction in rats
05 March 2012
Highlights: ► Using isoproterenol induced myocardial infarction rat models to elucidate the effect of coptisine and investigate its potential mechanism. ► Coptisine has strong antioxidant activity. ► ...
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Li-Li Gong,
Lian-Hua Fang,
Su-Bo Wang,
Jia-Lin Sun,
Hai-Lin Qin,
Xiao-Xiu Li,
Shou-Bao Wang,
Guan-Hua Du
et al.
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50-58
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A combination of secondhand cigarette smoke and Chlamydia pneumoniae accelerates atherosclerosis
14 March 2012
Highlights: ► We model the effect on atherosclerosis following exposure to smoke and Chlamydia. ► In combination, the two insults enhance atherosclerosis in ApoE knockout mice. ► They promote inflamma...
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Xiaoyan Zhao,
De-xiu Bu,
Kweku Hayfron,
Kent E. Pinkerton,
Charles L. Bevins,
Andrew Lichtman,
Jean Wiedeman
et al.
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59-66
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Increased expression of T cell immunoglobulin- and mucin domain-containing molecule-3 on natural killer cells in atherogenesis
05 March 2012
Highlights: ► Expression of Tim-3 increase on NK cells, but not T cells, in AS patients. ► Augmented expression of Tim-3 on NK cells correlates with risk factors of AS. ► Augmented expression of Tim-3...
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Nan Hou,
Di Zhao,
Ying Liu,
Lifen Gao,
Xiaohong Liang,
Xiao Liu,
Xiaoxiao Gai,
Xiaoning Zhang,
Faliang Zhu,
Mei Ni,
Yun Zhang,
Wensheng Sun,
Chunhong Ma
et al.
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67-73
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Lysophosphatidic acid causes endothelial dysfunction in porcine coronary arteries and human coronary artery endothelial cells
19 March 2012
Highlights: ► Lysophosphatidic acid reduces endothelium-dependent vasorelaxation in porcine coronary arteries. ► Lysophosphatidic acid decreases the expression of endothelial nitric oxide synthase in ...
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Chanygi Chen,
Lyssa N. Ochoa,
Anna Kagan,
Hong Chai,
Zhengdong Liang,
Peter H. Lin,
Qizhi Yao
et al.
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74-83
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Enhancer of polycomb1 lessens neointima formation by potentiation of myocardin-induced smooth muscle differentiation
09 March 2012
Highlights: ► Enhancer of polycomb1 (Epc1) attenuates VSMC proliferation. ► Epc1 induces VSMC differentiation. ► Epc1 interact with myocardin to activate smooth muscle 22α promoter activity. ► Epc1 ge...
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Hosouk Joung,
Jin-Sook Kwon,
Ju-Ryoung Kim,
Sera Shin,
Wanseok Kang,
Youngkeun Ahn,
Hyun Kook,
Hae Jin Kee
et al.
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84-91
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| Metabolism: Lipids, Lipoprotein, Carbohydrates, Homocysteine, Cholesterol |
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Article Title |
Author(s) |
Pages |
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Paraoxonase1 deficiency in mice is associated with hypotension and increased levels of 5,6-epoxyeicosatrienoic acid
27 February 2012
Highlights: ► Studying the role of PON1 in blood pressure (BP) regulation, using paraoxonase1 knockout (PON1KO) mice. ► Reduced BP observed in PON1KO is RAAS- and NO-independent. ► A direct, causal re...
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Aviva Gamliel-Lazarovich,
Zaid Abassi,
Soliman Khatib,
Hagai Tavori,
Jacob Vaya,
Michael Aviram,
Shlomo Keidar
et al.
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92-98
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Effect of an oral astaxanthin prodrug (CDX-085) on lipoprotein levels and progression of atherosclerosis in LDLR−/− and ApoE−/− mice
14 March 2012
Highlights: ► Oxidative stress and inflammation are key promoters of atherosclerosis and myocardial damage. ► The xanthophyll antioxidant protects LDL from oxidation and reduces primary thrombosis. ► ...
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Sung Kee Ryu,
Timothy J. King,
Kazutoshi Fujioka,
Jennifer Pattison,
Fredrick J. Pashkow,
Sotirios Tsimikas
et al.
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99-105
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| Clinical & Population Research |
| Imaging & Measurement of Vessel Health |
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Author(s) |
Pages |
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Characteristics of earlier atherosclerotic involvement in adolescent patients with Kawasaki disease and coronary artery lesions: Significance of gray scale median on B-mode ultrasound
29 February 2012
Abstract: Objective: To test the hypothesis that textural changes in the carotid intima–media complex (IMC) detected by B-mode ultrasound are associated with the difference of remodeling process in ea...
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Nobutaka Noto,
Tomoo Okada,
Yuriko Abe,
Michio Miyashita,
Hiroshi Kanamaru,
Kensuke Karasawa,
Mamoru Ayusawa,
Naokata Sumitomo,
Hideo Mugishima
et al.
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106-109
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Electrocardiographic abnormalities improve classification of coronary heart disease risk in women: Tehran Lipid and Glucose Study
02 March 2012
Highlights: ► We examined the added value of ECG abnormalities in risk stratification for coronary heart disease beyond the Framingham risk score. ► Among women, only in intermediate risk group, the E...
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Farzad Hadaegh,
Reza Mohebi,
Mohammadreza Bozorgmanesh,
Navid Saadat,
Farhad Sheikholeslami,
Fereidoun Azizi
et al.
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110-115
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High-sensitive Troponin I in acute cardiac conditions: Implications of baseline and sequential measurements for diagnosis of myocardial infarction
09 March 2012
Highlights: ► Baseline and sequential hsTnI was assessed in patients with acute cardiac condition and catheterization. ► hsTnI is a sensitive, albeit unspecific marker of myocardial infarction. ► Rele...
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Tobias Gassenmaier,
Stefan Buchner,
Christoph Birner,
Carsten G. Jungbauer,
Markus Resch,
Kurt Debl,
Dierk H. Endemann,
Guenter A.J. Riegger,
Petra Lehn,
Gerd Schmitz,
Andreas Luchner
et al.
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116-122
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Prognostic value of reverse left ventricular remodeling after primary angioplasty for STEMI
16 March 2012
Highlights: ► Reverse left ventricular remodeling after STEMI has not been fully evaluated. ► Reverse LV remodeling occurred in 49% of STEMI when primary PCI is systematically applied. ► Reverse LV re...
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Nazario Carrabba,
Guido Parodi,
Renato Valenti,
Angela Migliorini,
Benedetta Bellandi,
David Antoniucci.
et al.
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123-128
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Association of pericardial fat and coronary high-risk lesions as determined by cardiac CT
14 March 2012
Highlights: ► Pericardial fat is associated with coronary high-risk lesions by cardiac CT. ► Association is statistically independent of traditional risk factors including BMI. ► Pericardial fat discr...
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Christopher L. Schlett,
Maros Ferencik,
Matthias F. Kriegel,
Fabian Bamberg,
Brian B. Ghoshhajra,
Subodh B. Joshi,
John T. Nagurney,
Caroline S. Fox,
Quynh A. Truong,
Udo Hoffmann
et al.
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129-134
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| Genetics |
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Article Title |
Author(s) |
Pages |
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The 9p21 genetic variant is additive to carotid intima media thickness and plaque in improving coronary heart disease risk prediction in white participants of the Atherosclerosis Risk in Communities (ARIC) Study
20 February 2012
Highlights: ► CIMT/plaque and 9p21 SNP are known to be associated with CHD. ► CIMT/plaque and 9p21 SNP can improve CHD risk prediction. ► We now show that combining CIMT/plaque, 9p21 further marginall...
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Vijay Nambi,
Eric Boerwinkle,
Kim Lawson,
Ariel Brautbar,
Lloyd Chambless,
Nora Franeschini,
Kari E. North,
Salim S. Virani,
Aaron R. Folsom,
Christie M. Ballantyne
et al.
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135-137
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Genetic determinants of the ankle-brachial index: A meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium
23 February 2012
Highlights: ► Examined association of genetic variants with ankle brachial index (ABI). ► Studies were ethnically diverse, African-American and European ancestry. ► Variants in TCF7L2 and SYTL3 associ...
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Christina L. Wassel,
Claudia Lamina,
Vijay Nambi,
Stefan Coassin,
Kenneth J. Mukamal,
Santhi K. Ganesh,
David R. Jacobs,
Nora Franceschini,
George J. Papanicolaou,
Quince Gibson,
Lisa R. Yanek,
Pim van der Harst,
Jane F. Ferguson,
Dana C. Crawford,
Lindsay L. Waite,
Matthew A. Allison,
Michael H. Criqui,
Mary M. McDermott,
Reena Mehra,
L. Adrienne Cupples,
Shih-Jen Hwang,
Susan Redline,
Robert C. Kaplan,
Gerardo Heiss,
Jerome I. Rotter,
Eric Boerwinkle,
Herman A. Taylor,
Luis H. Eraso,
Margot Haun,
Mingyao Li,
Christa Meisinger,
Jeffrey R. O’Connell,
Alan R. Shuldiner,
Anne Tybjærg-Hansen,
Ruth Frikke-Schmidt,
Barbara Kollerits,
Barbara Rantner,
Benjamin Dieplinger,
Marietta Stadler,
Thomas Mueller,
Meinhard Haltmayer,
Peter Klein-Weigel,
Monika Summerer,
H.-Erich Wichmann,
Folkert W. Asselbergs,
Gerjan Navis,
Irene Mateo Leach,
Kristin Brown-Gentry,
Robert Goodloe,
Themistocles L. Assimes,
Diane M. Becker,
John P. Cooke,
Devin M. Absher,
Jeffrey W. Olin,
Braxton D. Mitchell,
Muredach P. Reilly,
Emile R. Mohler,
Kari E. North,
Alexander P. Reiner,
Florian Kronenberg,
Joanne M. Murabito
et al.
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138-147
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Lack of association between connexin40 polymorphisms and coronary artery disease
09 March 2012
Highlights: ► Human Cx40 is expressed under its promoter A in endothelial cells. ► Cx40 promoter A polymorphisms are not associated with coronary artery disease. ► Reduction of Cx40 expression by half...
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Anna Pfenniger,
Sander W. van der Laan,
Bernard Foglia,
Sylvie Dunoyer-Geindre,
Jacques-Antoine Haefliger,
Stephan Winnik,
François Mach,
Gerard Pasterkamp,
Richard W. James,
Brenda R. Kwak
et al.
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148-153
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Identification of genes affecting apolipoprotein B secretion following siRNA-mediated gene knockdown in primary human hepatocytes
09 March 2012
Highlights: ► siRNA-mediated gene knockdown in primary human hepatocytes was used to identify potential causal genes affecting lipid traits. ► Approximately 100 GWAS loci significantly affecting human...
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Xun Shen,
Wei Wang,
Liangsu Wang,
Caroline Houde,
Weizhen Wu,
Matt Tudor,
John R. Thompson,
Christine McCrary Sisk,
Brian Hubbard,
Jing Li
et al.
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154-157
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Effect of mutations in LDLR and PCSK9 genes on phenotypic variability in Tunisian familial hypercholesterolemia patients
14 March 2012
Highlights: ► Phenotypic expression in Tunisian familial hypercholesterolemia varied widely. ► We identified a new putative loss of function mutation in PCSK9 gene: p.P174S. ► Variants of PCSK9 and AP...
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Afef Slimani,
Awatef Jelassi,
Imen Jguirim,
Mohamed Najah,
Lamia Rebhi,
Asma Omezzine,
Faouzi Maatouk,
Khaldoun Ben Hamda,
Maha Kacem,
Jean-Pierre Rabès,
Marianne Abifadel,
Catherine Boileau,
Mustapha Rouis,
Mohamed Naceur Slimane,
Mathilde Varret
et al.
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158-166
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Vitamin D dependent effects of APOA5 polymorphisms on HDL cholesterol
19 March 2012
Highlights: ► A 25OHD receptor binding site modifying APOA5 promoter polymorphism was associated with lower HDL-C in 25OHD deficient individuals. ► Stronger interactions in subsamples evaluated in win...
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Brian H. Shirts,
Michael T. Howard,
Sandra J. Hasstedt,
M. Nazeem Nanjee,
Stacey Knight,
John F. Carlquist,
Jeffrey L. Anderson,
Paul N. Hopkins,
Steven C. Hunt
et al.
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167-174
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Genetic predisposition to coronary heart disease and stroke using an additive genetic risk score: A population-based study in Greece
19 March 2012
Highlights: ► We constructed a genetic risk score based on 9 “CHD-specific” SNPs from GWAS. ► We examined whether this genetic risk score (GRS) predicts incident CHD and stroke. ► We have used resourc...
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N. Yiannakouris,
M. Katsoulis,
V. Dilis,
L.D. Parnell,
D. Trichopoulos,
J.M. Ordovas,
A. Trichopoulou
et al.
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175-179
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Genetic and environmental influences on total plasma homocysteine and its role in coronary artery disease risk
19 March 2012
Highlights: ► Hyperhomocysteinemia is associated with increased risk of overall stenosis in the Lebanese population. ► Hyperhomocysteinemia increases the risk of mild and severe occlusion in major art...
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Michella Ghassibe-Sabbagh,
Daniel E. Platt,
Sonia Youhanna,
Antoine B. Abchee,
Krista Stewart,
Danielle A. Badro,
Marc Haber,
Angelique K. Salloum,
Bouchra Douaihy,
Hamid el Bayeh,
Raed Othman,
Nabil Shasha,
Samer Kibbani,
Elie Chammas,
Aline Milane,
Rita Nemr,
Yoichiro Kamatani,
Jörg Hager,
Jean-Baptiste Cazier,
Dominique Gauguier,
Pierre A. Zalloua,
FGENTCARD Consortium
et al.
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180-186
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Single polymorphism nucleotide rs1333049 on chromosome 9p21 is associated with carotid plaques but not with common carotid intima-media thickness in older adults. A combined analysis of the Three-City and the EVA studies
22 March 2012
Highlights: ► We studied the link between rs1333049 and subclinical atherosclerosis in older adults. ► Carotid plaques and intima-media thickness were assessed by ultrasound examination. ► Common caro...
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Matthieu Plichart,
Jean-Philippe Empana,
Jean-Charles Lambert,
Philippe Amouyel,
Laurence Tiret,
Luc Letenneur,
Claudine Berr,
Christophe Tzourio,
Pierre Ducimetière
et al.
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187-190
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| Intervention |
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Coronary plaque rupture in patients with myocardial infarction after noncardiac surgery: Frequent and dangerous
14 March 2012
Highlights: ► Nearly 50% of patients with acute coronary syndromes (ACS) after noncardiac surgery have evidence of coronary plaque rupture. ► The only independent predictor of plaque rupture in corona...
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Danielle Menosi Gualandro,
Carlos Augusto Campos,
Daniela Calderaro,
Pai Ching Yu,
Andre Coelho Marques,
Adriana Feio Pastana,
Pedro Alves Lemos,
Bruno Caramelli
et al.
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191-195
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| Epidemiology, Biomarkers, Nutrition |
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Author(s) |
Pages |
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Periodontitis and diabetes associations with measures of atherosclerosis and CHD
22 March 2012
Highlights: ► Severe periodontal disease and diabetes is associated with increased prevalence of IMT≥1, acoustic shadowing, and CHD. ► Diabetes alone is associated with increased odds for IMT>1mm, ...
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Janet H. Southerland,
Kevin Moss,
George W. Taylor,
James D. Beck,
James Pankow,
Pandu R. Gangula,
Steven Offenbacher
et al.
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196-201
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Correlates of endothelial function and the peak systolic blood pressure response to a graded maximal exercise test
13 February 2012
Highlights: ► BAR % change from baseline at 1min, fasting blood glucose, NOS3 −786 T>C, baseline NO, and age explain 24.1% of the peak SBP response to a GEST. ► Carriers of the NOS3 C minor/risk al...
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Kayla M. Olson,
Amanda L. Augeri,
Richard L. Seip,
Gregory J. Tsongalis,
Paul D. Thompson,
Linda S. Pescatello
et al.
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202-207
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Endothelial insulin receptor expression in human atherosclerotic plaques: Linking micro- and macrovascular disease in diabetes?
16 February 2012
Highlights: ► Insulin enhances capillary-like tube formation of human microvascular endothelial cells. ► Insulin receptors are highly expressed on endothelial cells of nascent microvessels within huma...
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K.L. Rensing,
J.H. von der Thüsen,
E.M. Weijers,
F.M. Houttuijn Bloemendaal,
G.W. van Lammeren,
A. Vink,
A.C. van der Wal,
V.W.M. van Hinsbergh,
C.M. van der Loos,
E.S. Stroes,
P. Koolwijk,
Th.B. Twickler
et al.
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208-215
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NT-proBNP is associated with fibulin-1 in Africans: The SAfrEIC study
20 February 2012
Highlights: ► We explored NT-proBNP and fibulin-1 in Africans and Caucasians. ► A positive relationship exists between NT-proBNP and fibulin-1 in African men. ► This association remains independent of...
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R. Kruger,
R. Schutte,
H.W. Huisman,
W.S. Argraves,
L.M. Rasmussen,
M.H. Olsen,
A.E. Schutte
et al.
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216-221
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Postprandial accumulation of chylomicrons and chylomicron remnants is determined by the clearance capacity
27 February 2012
Highlights: ► Accumulation of lipids in the blood after a meal predicts cardiovascular events. ► We tested the relation between fasting and non-fasting triglycerides levels. ► Secretion of triglycerid...
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Martin Adiels,
Niina Matikainen,
Jukka Westerbacka,
Sanni Söderlund,
Thomas Larsson,
Sven-Olof Olofsson,
Jan Borén,
Marja-Riitta Taskinen
et al.
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222-228
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FABP4 predicts atherogenic dyslipidemia development. The PREDIMED study
15 March 2012
Highlights: ► FABP4 was considered an emerging factor of metabolic risk. ► Individuals with atherogenic dyslipidemia have higher FABP4 plasma concentrations. ► We observed that elevated FABP4 plasma c...
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Anna Cabré,
Nancy Babio,
Iolanda Lázaro,
Mònica Bulló,
Ana Garcia-Arellano,
Lluís Masana,
Jordi Salas-Salvadó
et al.
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229-234
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Salt intake determines retinal arteriolar structure in treatment resistant hypertension independent of blood pressure
05 March 2012
Highlights: ► We performed in vivo measurements of retinal arteriolars with scanning laser doppler flowmetry in patients with treatment resistant hypertension. ► Wall to lumen ratio, wall thickness an...
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Ulrike Raff,
Joanna M. Harazny,
Stephanie I. Titze,
Bernhard M. Schmidt,
Georg Michelson,
Roland E. Schmieder
et al.
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235-240
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Associations between serum lipoprotein(a) levels and the severity of coronary and aortic atherosclerosis
05 March 2012
Abstract: To elucidate the associations between Lp(a) levels and coronary and aortic atherosclerosis, we performed aortic MRI in 143 patients undergoing coronary angiography. Severity of aortic athero...
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Yukihiko Momiyama,
Reiko Ohmori,
Zahi A. Fayad,
Nobukiyo Tanaka,
Ryuichi Kato,
Hiroaki Taniguchi,
Masayoshi Nagata,
Fumitaka Ohsuzu
et al.
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241-244
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Associations between alcohol consumption and selected cytokines in a Swiss population-based sample (CoLaus study)
15 March 2012
Highlights: ► Moderate alcohol consumption is associated with lower levels of interleukin 6 and tumor necrosis factor-α. ► This effect occurs irrespective of the type of alcohol consumed (wine, beer o...
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Pedro Marques-Vidal,
Murielle Bochud,
François Bastardot,
Roland von Känel,
François Ferrero,
Jean-Michel Gaspoz,
Fred Paccaud,
Adrian Urwyler,
Thomas Lüscher,
Christoph Hock,
Gérard Waeber,
Martin Preisig,
Peter Vollenweider
et al.
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245-250
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Premature myocardial infarction is associated with low serum levels of Wnt-1
05 March 2012
Highlights: ► Young myocardial infarction patients (≤40years) show decreased Wnt-1 levels. ► Premature CAD patients show elevated levels of the Wnt-1 antagonist Dkk-1. ► Low Wnt-1 levels are associate...
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Georg Goliasch,
Franz Wiesbauer,
Stefan P. Kastl,
Katharina M. Katsaros,
Hermann Blessberger,
Gerald Maurer,
Martin Schillinger,
Kurt Huber,
Johann Wojta,
Walter S. Speidl
et al.
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251-256
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Relation of total and free testosterone and sex hormone-binding globulin with cardiovascular risk factors in men aged 24–45 years. The Cardiovascular Risk in Young Finns Study
15 March 2012
Highlights: ► The study cohort consisted of 24–45-year-old Finnish men. ► We studied the relations of testosterone and SHBG with cardiovascular risk factors. ► Lower levels of testosterone and SHBG ar...
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Sonja Firtser,
Markus Juonala,
Costan G. Magnussen,
Antti Jula,
Britt-Marie Loo,
Jukka Marniemi,
Jorma S.A. Viikari,
Jorma Toppari,
Antti Perheentupa,
Nina Hutri-Kähönen,
Olli T. Raitakari
et al.
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257-262
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Differential proteomic distribution of TTR (pre-albumin) forms in serum and HDL of patients with high cardiovascular risk
16 March 2012
Highlights: ► TTR shows important changes in serum and HDL proteomes of AMI- and FH-patients. ► Inverse relationship between tTTR levels and cardiovascular risk factors after AMI. ► AMI-patients with ...
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Judit Cubedo,
Teresa Padró,
Rodrigo Alonso,
Juan Cinca,
Pedro Mata,
Lina Badimon
et al.
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263-269
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Flavonols intake and the risk of coronary heart disease: a meta-analysis of cohort studies
19 March 2012
Abstract: Objective: Prospective cohort are inconsistent regarding the association between flavonols intake and the risk of coronary heart disease (CHD). The aim was to perform a meta-analysis to dete...
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Ze-Mu Wang,
Zhen-Lin Nie,
Bo Zhou,
Xiao-Qing Lian,
Huan Zhao,
Wei Gao,
Yong-Sheng Wang,
En-Zhi Jia,
Lian-Sheng Wang,
Zhi-Jian Yang
et al.
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270-273
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Atherosclerosis risk in HIV-infected patients: The influence of hepatitis C virus co-infection
14 March 2012
Abstract: Background: The influence of hepatitis C virus (HCV) infection on atherosclerosis risk in HIV-infected patients has not been adequately evaluated in real-life situations. Objectives and meth...
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Philippe Sosner,
Marc Wangermez,
Carine Chagneau-Derrode,
Gwenaël Le Moal,
Christine Silvain
et al.
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274-277
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Inverse association between the existence of coronary artery disease and progression of abdominal aortic aneurysm
19 March 2012
Highlights: ► Retrospective cohort study in 665 Japanese patients undergone elective AAA repair was performed. ► An inverse association between the existence of CAD and progression of AAA was identifi...
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Atsuko Nakayama,
Hiroyuki Morita,
Tetsuro Miyata,
Jiro Ando,
Hideo Fujita,
Hiroshi Ohtsu,
Takafumi Akai,
Katsuyuki Hoshina,
Masatoshi Nagayama,
Shuichiro Takanashi,
Tetsuya Sumiyoshi,
Ryozo Nagai
et al.
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278-283
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High sodium intake adversely affects oxidative-inflammatory response, cardiac remodelling and mortality after myocardial infarction
21 March 2012
Highlights: ► The effect of sodium intake on the outcome after myocardial infarction is unknown. ► High sodium intake favors inflammation and ventricular remodeling. ► High sodium intakers have higher...
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Ana Paula R. Costa,
Rafaela C.S. de Paula,
Guilherme F. Carvalho,
Juliana P. Araújo,
Joalbo M. Andrade,
Osorio L.R. de Almeida,
Eliana C. de Faria,
Wladimir M. Freitas,
Otavio R. Coelho,
Jose A.F. Ramires,
Jose C. Quinaglia e Silva,
Andrei C. Sposito,
on behalf of the Brasilia Heart Study Group
et al.
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284-291
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High-dose rosiglitazone is pro-atherogenic in cholesterol-fed rabbits
29 February 2012
Rosiglitazone (Avendia) is an agonist of peroxisome proliferator activated receptor gamma (PPARγ) and has been widely used for the treatment of type 2 diabetes in US due to its effect of improving ins...
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Yanli Wang,
Fang Cheng,
Yulong Chen,
Yafen Li,
Sihai Zhao,
Qi Yu,
Jianglin Fan,
Enqi Liu
et al.
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292-294
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Low rate of detection of active cytomegalovirus (CMV) infection early following acute myocardial infarction
15 March 2012
Inflammation plays a crucial role in the development of cardiovascular diseases. Several lines of clinical, epidemiological and experimental evidences suggest a role for cytomegalovirus (CMV), whose p...
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Julio Núñez,
Marifina Chilet,
Maria L. Blasco,
María A. Clari,
Rafael Sanjuan,
Beatriz Muñoz-Cobo,
Vicent Bodí,
Elisa Costa,
Dayana Bravo,
Juan Sanchis,
Gema Miñana,
David Navarro
et al.
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295-297
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