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Editorial Board page iii Full-Text PDF (43 KB)
Reviews
Elevated heart rate and cardiovascular outcomes in patients with coronary artery disease: Clinical evidence and pathophysiological mechanisms, 12 February 2010 Chim C. Lang, Sandeep Gupta, Paul Kalra, Bernard Keavney, Ian Menown, Chris Morley, Sandosh Padmanabhan pages 1-8 Abstract | Full Text | Full-Text PDF (279 KB)
Association between change in plasma triglyceride levels and risk of stroke and carotid atherosclerosis: Systematic review and meta-regression analysis, 11 May 2010 Julien Labreuche, Dominique Deplanque, Pierre-Jean Touboul, Eric Bruckert, Pierre Amarenco pages 9-15 Abstract | Full Text | Full-Text PDF (255 KB) | Add-Ons
Genetic and epigenetic mechanisms and their possible role in abdominal aortic aneurysm, 29 March 2010 Smriti M. Krishna, Anthony E. Dear, Paul E. Norman, Jonathan Golledge pages 16-29 Abstract | Full Text | Full-Text PDF (520 KB)
Letter to the Editor
Reduction of endoplasmic reticulum stress—A novel mechanism of action of statins in the protection against atherosclerosis, 31 May 2010 Ikaro Breder, Andressa Coope, Ana Paula Arruda, Daniela Razolli, Marciane Milanski, Gabriel de Gabriel Dorighello, Helena C.F. de Oliveira, Lício A. Velloso pages 30-31 Abstract | Full Text | Full-Text PDF (532 KB)
Invited Commentaries
Animal models of atherosclerosis: More than mice, 20 July 2010 Lisa R. Tannock, Victoria L. King pages 32-33 Full Text | Full-Text PDF (78 KB)
Eicosapentaenoic acid (EPA) from highly concentrated n-3 fatty acid ethyl esters is incorporated into advanced atherosclerotic plaques and higher plaque EPA is associated with decreased plaque inflammation and increased stability, 20 July 2010 Antonis Zampelas pages 34-35 Full Text | Full-Text PDF (82 KB)
Induced pluripotent stem (iPS) cells and endothelial cell generation: SIRT-ainly a good idea!, 20 July 2010 Rute Moura, Gian Paolo Fadini, Marc Tjwa pages 36-39 Full Text | Full-Text PDF (159 KB)
Newly appreciated therapeutic effect of GLP-1 receptor agonists: Reduction in postprandial lipemia, 20 July 2010 Robert H.J. Bandsma, Gary F. Lewis pages 40-41 Full Text | Full-Text PDF (86 KB)
Basic Research
Vascular Biology, Hemostasis and Oxidative Stress
Sirt1 plays an important role in mediating greater functionality of human ES/iPS-derived vascular endothelial cells, 20 May 2010 Koichiro Homma, Masakatsu Sone, Daisuke Taura, Kenichi Yamahara, Yutaka Suzuki, Kazutoshi Takahashi, Takuhiro Sonoyama, Megumi Inuzuka, Yasutomo Fukunaga, Naohisa Tamura, Hiroshi Itoh, Shinya Yamanaka, Kazuwa Nakao pages 42-47 Abstract | Full Text | Full-Text PDF (1408 KB) | Add-Ons
Atherosclerosis in Octodon degus (degu) as a model for human disease, 15 July 2010 Reynold Homan, Jeffrey C. Hanselman, Sandra Bak-Mueller, Michelle Washburn, Patrick Lester, Heather E. Jensen, Stephen L. Pinkosky, Christine Castle, Bruce Taylor pages 48-54 Abstract | Full Text | Full-Text PDF (481 KB) | Add-Ons
Heart rate reduction with ivabradine improves erectile dysfunction in parallel to decrease in atherosclerotic plaque load in ApoE-knockout mice, 29 March 2010 Magnus Baumhäkel, Florian Custodis, Nils Schlimmer, Ulrich Laufs, Michael Böhm pages 55-62 Abstract | Full Text | Full-Text PDF (500 KB) | Add-Ons
Human umbilical cord blood endothelial progenitor cells decrease vein graft neointimal hyperplasia in SCID mice, 10 May 2010 Shoukang Zhu, Anuj Malhotra, Lisheng Zhang, Shanming Deng, Taifang Zhang, Neil J. Freedman, Robert Storms, Karsten Peppel, Pascal J. Goldschmidt-Clermont, Chunming Dong pages 63-69 Abstract | Full Text | Full-Text PDF (831 KB) | Add-Ons
Chronic infusion of salusin-α and -β exerts opposite effects on atherosclerotic lesion development in apolipoprotein E-deficient mice, 31 May 2010 Masaharu Nagashima, Takuya Watanabe, Yuji Shiraishi, Ryou Morita, Michishige Terasaki, Shigeko Arita, Shigeki Hongo, Kengo Sato, Masayoshi Shichiri, Akira Miyazaki, Tsutomu Hirano pages 70-77 Abstract | Full Text | Full-Text PDF (990 KB)
Vascular superoxide production by endothelin-1 requires Src non-receptor protein tyrosine kinase and MAPK activation, 31 May 2010 Miguel Romero, Rosario Jiménez, Manuel Sánchez, Rocío López-Sepúlveda, Antonio Zarzuelo, Juan Tamargo, Francisco Pérez-Vizcaíno, Juan Duarte pages 78-85 Abstract | Full Text | Full-Text PDF (400 KB) | Add-Ons
Pomegranate juice (PJ) consumption antioxidative properties on mouse macrophages, but not PJ beneficial effects on macrophage cholesterol and triglyceride metabolism, are mediated via PJ-induced stimulation of macrophage PON2, 31 May 2010 Mira Rosenblat, Nina Volkova, Michael Aviram pages 86-92 Abstract | Full Text | Full-Text PDF (396 KB) | Add-Ons
Oats (Avena sativa) reduce atherogenesis in LDL-receptor-deficient mice, 31 May 2010 K.E. Andersson, K.A. Svedberg, M.W. Lindholm, R. Öste, P. Hellstrand pages 93-99 Abstract | Full Text | Full-Text PDF (389 KB) | Add-Ons
The androgen derivative 5α-androstane-3β,17β-diol inhibits tumor necrosis factor α and lipopolysaccharide induced inflammatory response in human endothelial cells and in mice aorta, 18 June 2010 Giuseppe Danilo Norata, Paola Cattaneo, Angelo Poletti, Alberico Luigi Catapano pages 100-106 Abstract | Full Text | Full-Text PDF (542 KB) | Add-Ons
Dietary rice protein isolate attenuates atherosclerosis in apoE-deficient mice by upregulating antioxidant enzymes, 08 June 2010 Ramona L. Burris, Cheng-Hui Xie, Prajitha Thampi, Xianli Wu, Stepan B. Melnyk, Shanmugam Nagarajan pages 107-115 Abstract | Full Text | Full-Text PDF (447 KB)
Effect of endothelial cell proliferation on atherogenesis: A role of p21Sdi/Cip/Waf1 in monocyte adhesion to endothelial cells, 05 July 2010 Hiyo Obikane, Yoshimitsu Abiko, Hikaru Ueno, Yoshiaki Kusumi, Mariko Esumi, Masako Mitsumata pages 116-122 Abstract | Full Text | Full-Text PDF (580 KB) | Add-Ons
Reduction of PKCβII activity in smooth muscle cells attenuates acute arterial injury, 01 July 2010 Chun Huang, Jong Sun Chang, Yunlu Xu, Qing Li, Yu Shan Zou, Shi-Fang Yan pages 123-130 Abstract | Full Text | Full-Text PDF (655 KB) | Add-Ons
Metabolism: Lipids, Lipoproteins, Carbohydrates, Homocysteine and Cholesterol
Beneficial direct adipotropic actions of pitavastatin in vitro and their manifestations in obese mice, 13 May 2010 Yasuhiro Ishihara, Koji Ohmori, Mizuki Mizukawa, Arif Ul. Hasan, Takahisa Noma, Masakazu Kohno pages 131-138 Abstract | Full Text | Full-Text PDF (1070 KB) | Add-Ons
LXRα regulates human CETP expression in vitro and in transgenic mice, 24 May 2010 Shoko Honzumi, Akiko Shima, Ayano Hiroshima, Tadashi Koieyama, Naoko Ubukata, Naoki Terasaka pages 139-145 Abstract | Full Text | Full-Text PDF (372 KB) | Add-Ons
Anti-atherogenic effect of BHB-TZD having inhibitory activities on cyclooxygenase and 5-lipoxygenase in hyperlipidemic mice, 31 May 2010 Jae-Hoon Choi, Hyung Jun Jeon, Jong-Gil Park, Seong Keun Sonn, Mi-Ran Lee, Mi-Ni Lee, Hye Jin You, Geun-Young Kim, Jae-Hong Kim, Mun Han Lee, Oh-Seung Kwon, Ki-Hoan Nam, Hyoung-Chin Kim, Tae-Sook Jeong, Woo Song Lee, Goo Taeg Oh pages 146-152 Abstract | Full Text | Full-Text PDF (535 KB) | Add-Ons
Specific binding of hypochlorite-oxidized HDL to platelet CD36 triggers proinflammatory and procoagulant effects, 31 May 2010 Alice Assinger, Franz Koller, Werner Schmid, Maria Zellner, Rita Babeluk, Elisabeth Koller, Ivo Volf pages 153-160 Abstract | Full Text | Full-Text PDF (359 KB) | Add-Ons
Clinical and Population Research
Imaging and Measurement of Vessel Health
Enhanced matrix-degrading proteolytic activity within the thin thrombus-covered wall of human abdominal aortic aneurysms, 31 May 2010 Ireneusz Wiernicki, Ewa Stachowska, Krzysztof Safranow, Miloslaw Cnotliwy, Marta Rybicka, Mariusz Kaczmarczyk, Piotr Gutowski pages 161-165 Abstract | Full Text | Full-Text PDF (235 KB)
The aorta wall of patients presenting to the emergency department with acute myocardial infarction by cardiac magnetic resonance, 28 June 2010 John F. Heitner, Geetha P. Bhumireddy, Peter J. Cawley, Igor Klem, Patel Manesh R., Anna Lisa Crowley, Jonathan W. Weinsaft, Michael Elliott, Michele Parker, Sorin Brener, Robert M. Judd, Raymond J. Kim pages 166-170 Abstract | Full Text | Full-Text PDF (306 KB)
Association of monocyte subsets with vulnerability characteristics of coronary plaques as assessed by 64-slice multidetector computed tomography in patients with stable angina pectoris, 31 May 2010 Manabu Kashiwagi, Toshio Imanishi, Hiroto Tsujioka, Hideyuki Ikejima, Akio Kuroi, Yuichi Ozaki, Kohei Ishibashi, Kenichi Komukai, Takashi Tanimoto, Yasushi Ino, Hironori Kitabata, Kumiko Hirata, Takashi Akasaka pages 171-176 Abstract | Full Text | Full-Text PDF (194 KB)
Carotid distension and distensibility impairment in individuals affected by familial combined hyperlipidemia, 09 June 2010 Tiziana Montalcini, Gaetano Gorgone, Carmine Gazzaruso, Arturo Pujia pages 177-180 Abstract | Full Text | Full-Text PDF (109 KB)
In vivo optical molecular imaging of matrix metalloproteinase activity in abdominal aortic aneurysms correlates with treatment effects on growth rate, 14 June 2010 Rahul A. Sheth, Marco Maricevich, Umar Mahmood pages 181-187 Abstract | Full Text | Full-Text PDF (355 KB)
Passive leg raising induced brachial artery dilation: Is an old technique a simpler method to measure endothelial function?, 18 June 2010 Haroon Kamran, Louis Salciccioli, Vinod Namana, Bhuvaneshwari Venkatesan, Casey Santana, Mark Stewart, Jason M. Lazar pages 188-192 Abstract | Full Text | Full-Text PDF (218 KB)
Genetics
Single variants can explain the association between coronary heart disease and haplotypes in the apolipoprotein(a) locus, 02 June 2010 Dov Shiffman, Judy Z. Louie, Charles M. Rowland, Mary J. Malloy, John P. Kane, James J. Devlin pages 193-196 Abstract | Full Text | Full-Text PDF (286 KB) | Add-Ons
Silencing of the F11R gene reveals a role for F11R/JAM-A in the migration of inflamed vascular smooth muscle cells and in atherosclerosis, 07 June 2010 Bani M. Azari, Jonathan D. Marmur, Moro O. Salifu, Erdal Cavusoglu, Yigal H. Ehrlich, Elizabeth Kornecki, Anna Babinska pages 197-205 Abstract | Full Text | Full-Text PDF (4531 KB) | Add-Ons
Angiotensin II induces C-reactive protein expression through ERK1/2 and JNK signaling in human aortic endothelial cells, 10 June 2010 Chunjie Han, Juntian Liu, Xiaofang Liu, Ming Li pages 206-212 Abstract | Full Text | Full-Text PDF (454 KB)
Association between aldehyde dehydrogenase 2 genetic polymorphism and serum lipids or lipoproteins: A meta-analysis of seven East Asian populations, 14 June 2010 Pan-Pan Hao, Li Xue, Xing-Li Wang, Yu-Guo Chen, Jia-Li Wang, Wen-Qing Ji, Feng Xu, Shu-Jian Wei, Yun Zhang pages 213-216 Full Text | Full-Text PDF (180 KB)
Intervention
Exenatide suppresses postprandial elevations in lipids and lipoproteins in individuals with impaired glucose tolerance and recent onset type 2 diabetes mellitus, 17 June 2010 Eric A. Schwartz, Juraj Koska, Michael P. Mullin, Iyad Syoufi, Dawn C. Schwenke, Peter D. Reaven pages 217-222 Abstract | Full Text | Full-Text PDF (242 KB) | Add-Ons
One-year treatment with exenatide vs. Insulin Glargine: Effects on postprandial glycemia, lipid profiles, and oxidative stress, 24 May 2010 Mathijs C. Bunck, Anja Cornér, Bjorn Eliasson, Robert J. Heine, Rimma M. Shaginian, Yan Wu, Ping Yan, Ulf Smith, Hannele Yki-Järvinen, Michaela Diamant, Marja-Riitta Taskinen pages 223-229 Abstract | Full Text | Full-Text PDF (218 KB) | Add-Ons
Exercise training accelerates the removal from plasma of LDL-like nanoemulsion in moderately hypercholesterolemic subjects, 07 June 2010 Elisabeth S. Ficker, Raul C. Maranhão, Ana P.M. Chacra, Vanessa C. Neves, Carlos E. Negrão, Vanessa C.N. Martins, Carmen G.C. de M. Vinagre pages 230-236 Abstract | Full Text | Full-Text PDF (194 KB)
Correlation between circulating adiponectin levels and coronary plaque regression during aggressive lipid-lowering therapy in patients with acute coronary syndrome: Subgroup analysis of JAPAN-ACS study, 31 May 2010 Taiki Ohashi, Rei Shibata, Takeshi Morimoto, Masaaki Kanashiro, Hideki Ishii, Satoshi Ichimiya, Takafumi Hiro, Katsumi Miyauchi, Yoshihisa Nakagawa, Masakazu Yamagishi, Yukio Ozaki, Takeshi Kimura, Hiroyuki Daida, Toyoaki Murohara, Masunori Matsuzaki pages 237-242 Abstract | Full Text | Full-Text PDF (184 KB) | Add-Ons
Three-month treatment with pioglitazone reduces circulating levels of thiobarbituric acid-reacting substances, a marker of reactive oxidative stress, without change in body mass index, in Japanese patients with type 2 diabetes, 14 June 2010 Hideaki Nakatsuji, Ken Kishida, Tohru Funahashi, Iichiro Shimomura, The Senri Study II Group pages 243-245 Full Text | Full-Text PDF (148 KB)
Plasma PCSK9 is increased by Fenofibrate and Atorvastatin in a non-additive fashion in diabetic patients, 12 July 2010 P. Costet, M.M. Hoffmann, B. Cariou, B. Guyomarc’h Delasalle, T. Konrad, K. Winkler pages 246-251 Abstract | Full Text | Full-Text PDF (173 KB)
Epidemiology, Biomarkers and Nutrition
Eicosapentaenoic acid (EPA) from highly concentrated n−3 fatty acid ethyl esters is incorporated into advanced atherosclerotic plaques and higher plaque EPA is associated with decreased plaque inflammation and increased stability, 09 June 2010 Abbie L. Cawood, Ren Ding, Frances L. Napper, Ruth H. Young, Jennifer A. Williams, Matthew J.A. Ward, Ola Gudmundsen, Runar Vige, Simon P.K. Payne, Shu Ye, Ciff P. Shearman, Patrick J. Gallagher, Robert F. Grimble, Philip C. Calder pages 252-259 Abstract | Full Text | Full-Text PDF (192 KB)
Associations between dietary patterns and flow cytometry-measured biomarkers of inflammation and cellular activation in the Atherosclerosis Risk in Communities (ARIC) Carotid Artery MRI Study, 01 June 2010 Jennifer A. Nettleton, Nena Matijevic, Jack L. Follis, Aaron R. Folsom, Eric Boerwinkle pages 260-267 Abstract | Full Text | Full-Text PDF (138 KB) | Add-Ons
Cysteinemia, rather than homocysteinemia, is associated with plasma apolipoprotein A-I levels in hyperhomocysteinemia: Lipid metabolism in cystathionine β-synthase deficiency, 31 May 2010 Mario Nuño-Ayala, Natalia Guillén, María A. Navarro, Jose M. Lou-Bonafonte, Carmen Arnal, Sonia Gascón, Cristina Barranquero, Javier Godino, María Royo-Cañas, Alfonso J. Sarría, Mario A. Guzmán, Esther Hernandez, Miguel A. Bregante, María A. García-Gimeno, Jesús Osada pages 268-273 Abstract | Full Text | Full-Text PDF (329 KB) | Add-Ons
Increased visceral adipose tissue mass is associated with increased C-reactive protein in patients with manifest vascular diseases, 24 May 2010 Daniël R. Faber, Yolanda van der Graaf, Jan Westerink, Frank L.J. Visseren pages 274-280 Abstract | Full Text | Full-Text PDF (137 KB)
Alcohol consumption and risk of recurrent cardiovascular events and mortality in patients with clinically manifest vascular disease and diabetes mellitus: The Second Manifestations of ARTerial (SMART) disease study, 31 May 2010 J.W.J. Beulens, A. Algra, S.S. Soedamah-Muthu, F.L.J. Visseren, D.E. Grobbee, Y. van der Graaf, on behalf of the SMART Study Group pages 281-286 Abstract | Full Text | Full-Text PDF (123 KB)
Usefulness of the triglyceride to high-density lipoprotein cholesterol ratio for predicting mortality risk in type 2 diabetes: Role of kidney dysfunction, 01 June 2010 Giacomo Zoppini, Giovanni Targher, Carlo Negri, Vincenzo Stoico, Maria Luisa Gemma, Enzo Bonora pages 287-291 Abstract | Full Text | Full-Text PDF (107 KB)
Autonomic nervous system, inflammation and preclinical carotid atherosclerosis in depressed subjects with coronary risk factors, 01 June 2010 Carmine Pizzi, Lamberto Manzoli, Stefano Mancini, Gigliola Bedetti, Fiorella Fontana, Grazia Maria Costa pages 292-298 Abstract | Full Text | Full-Text PDF (136 KB)
Effects of low serum triglyceride on stroke mortality: A prospective follow-up study, 03 June 2010 Wi-Sun Ryu, Seung-Hoon Lee, Chi Kyung Kim, Beom Joon Kim, Byung-Woo Yoon pages 299-304 Abstract | Full Text | Full-Text PDF (196 KB)
Subclinical peripheral arterial disease in rheumatoid arthritis, 31 May 2010 Kimon S. Stamatelopoulos, George D. Kitas, Christos M. Papamichael, Katerina Kyrkou, Evangelia Zampeli, Kalliopi Fragiadaki, Vasileios F. Panoulas, Myron Mavrikakis, Petros P. Sfikakis pages 305-309 Abstract | Full Text | Full-Text PDF (119 KB)
Dehydroepiandrosterone sulfate is inversely associated with sex-dependent diverse carotid atherosclerosis regardless of endothelial function, 03 June 2010 Sumiko Yoshida, Ken-ichi Aihara, Hiroyuki Azuma, Ryoko Uemoto, Yuka Sumitomo-Ueda, Shusuke Yagi, Yasumasa Ikeda, Takashi Iwase, Susumu Nishio, Hiromi Kawano, Junko Miki, Hirotsugu Yamada, Yoichiro Hirata, Masashi Akaike, Masataka Sata, Toshio Matsumoto pages 310-315 Abstract | Full Text | Full-Text PDF (146 KB)
Occult impaired glucose regulation in patients with atherosclerosis is associated to the number of affected vascular districts and inflammation, 16 June 2010 Stefano Rizza, Marina Cardellini, Eugenio Martelli, Ottavia Porzio, Chiara Pecchioli, Antonio Nicolucci, Nikolaus Marx, Davide Lauro, Arnaldo Ippoliti, Franco Romeo, Renato Lauro, Massimo Federici pages 316-320 Abstract | Full Text | Full-Text PDF (160 KB) | Add-Ons
Helicobacter pylori cytotoxin-associated gene-A antibodies do not predict complications or death in type 2 diabetes: The Fremantle Diabetes Study, 09 June 2010 pages 321-326 Full-Text PDF (147 KB)
Arterial stiffness is associated with low thigh muscle mass in middle-aged to elderly men, 16 June 2010 Masayuki Ochi, Katsuhiko Kohara, Yasuharu Tabara, Tomoko Kido, Eri Uetani, Namiko Ochi, Michiya Igase, Tetsuro Miki pages 327-332 Abstract | Full Text | Full-Text PDF (225 KB) | Add-Ons
Increased levels of thioredoxin in patients with abdominal aortic aneurysms (AAAs). A potential link of oxidative stress with AAA evolution, 08 July 2010 R. Martinez-Pinna, J.S. Lindholt, L.M. Blanco-Colio, T. Dejouvencel, J. Madrigal-Matute, P. Ramos-Mozo, M. Vega de Ceniga, J.B. Michel, J. Egido, O. Meilhac, J.L. Martin-Ventura pages 333-338 Abstract | Full Text | Full-Text PDF (298 KB) | Add-Ons
Acute effects of whey protein isolate on cardiovascular risk factors in overweight, post-menopausal women, 21 June 2010 Sebely Pal, Vanessa Ellis, Suleen Ho pages 339-344 Abstract | Full Text | Full-Text PDF (180 KB)
Arterial stiffness and declines in individuals with normal renal function/early chronic kidney disease, 01 July 2010 Hirofumi Tomiyama, Hirofumi Tanaka, Hideki Hashimoto, Chisa Matsumoto, Mari Odaira, Jiko Yamada, Masanobu Yoshida, Kazuki Shiina, Mikio Nagata, Akira Yamashina pages 345-350 Abstract | Full Text | Full-Text PDF (129 KB)
Decreased serum levels of thioredoxin in patients with coronary artery disease plus hyperhomocysteinemia is strongly associated with the disease severity, 01 July 2010 Yunfei Wu, Lijuan Yang, Liangwei Zhong pages 351-355 Abstract | Full Text | Full-Text PDF (420 KB)
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